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For PDF or hard copy of any publication please contact Kelly Case, ksc7@cornell.edu.

2009

Cohen, R., A. Torres, H-T Ma, D. Holowka and B. Baird: Ca2+ Waves Initiate Antigen-Stimulated Ca2+ Responses in Mast Cells.  J. Immunol. 183(10): 6478-6488, 2009.

Haka, A.S., I. Grosheva, E. Chiang, A.R. Buxbaum, B.A. Baird, L.M. Pierini and F.R. Maxfield: Macrophages Create an Acidic Extracellular Hydrolytic Compartment to Digest Aggregated Lipoproteins.  Mol. Biol. Cell, in press 2009.

Rastogi, A., S. Nad, M. Tanaka, N. Da Mota, M. Tague, B.A. Baird, H.D. Abruna and C.K. Ober: Preventing Non-Specific Adsorption on Polymer Brush Covered Gold Electrodes Using a Modified ATRP Initiator.  Biomacromolecules 10(10): 2750-2758, 2009. 

Han, X., N.L. Smith, D. Sil, D.A. Holowka, F.W. McLafferty and B.A. Baird: IgE Receptor-Mediated Alteration of Membrane-Cytoskeleton Interactions Revealed by Mass Spectrometric Analysis of Detergent-Resistant Membranes.  Biochemistry 48(27): 6540-6550, 2009.

Hammond, S., A. Wagenknecht-Wiesner, S.L. Veatch, D. Holowka and B. Baird: Roles for SH2 and SH3 domains in Lyn kinase association with activated FceRI in RBL mast cells revealed by patterned surface analysis.  J. Struct. Biol. 168(1): 161-167, 2009.

Vasudevan, L., A. Jeromin, L. Volpicelli-Daley, P. De Camilli, D. Holowka and B. Baird. The beta- and gamma-isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells.  J. Cell Sci. 122(14): 2567-2574, 2009.

Hammond, S., D. Holowka and B. Baird. Membrane Compartments Related to Signaling and Trafficking in Immune Cells. In Wiley Encyclopedia of Chemical Biology, 4 Volume Set (Ed. T.P. Begley) Wiley InterScience; Vol. 2, pp. 718-728, January 2009.

Calloway, N., M. Vig, J.-P. Kinet, D. Holowka and B. Baird. Molecular Clustering of STIM1 with Orai1/CRACM1 at the Plasma Membrane Depends Dynamically on Depletion of Ca2+ Stores and on Electrostatic Interactions. Mol. Biol. Cell 20(1): 389-399, 2009.

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2008

Torres, A.J., L. Vasudevan, D. Holowka and B. Baird. Focal Adhesion Proteins Connect IgE Receptors to the Cytoskeleton as Revealed by Micropatterned Ligand Arrays. PNAS, 105(45): 17238-17244, 2008.

Sannigrahi, B., D. Sil, B. Baird, X.Q. Wang and I.M. Khan. Synthesis and Characterization of a,w-bi[2,4-dinitrophenyl (DNP)] poly(2-methoxystyrene) Functional Polymers. Initial Evaluation of the Interaction of the Functional Polymers with RBL Mast Cells. J. Macromol. Sci. (Part A: Pure & Appl. Chem.) 45(8): 664-671, 2008.

Veatch, S., P. Cicuta, P. Sengupta, A. Honerkamp-Smith, D. Holowka and B. Baird. Critical Fluctuations in Plasma Membrane Vesicles. ACS Chem. Biol. 3(5): 287-293, 2008.

Torres, A.J., M. Wu, D. Holowka and B. Baird. Nanobiotechnology and Cell Biology: Micro- and Nanofabricated Surfaces to Investigate Receptor-Mediated Signaling. Annu. Rev. Biophys. 37: 265-288, 2008.

Sengupta, P., A. Hammond, D. Holowka and B. Baird. Structural determinants for partitioning of lipids and proteins between coexisting fluid phases in giant plasma membrane vesicles. Biochim. Biophys. Acta 1778(1): 20-32, 2008.

Das, R., E. Baird, S. Allen, B. Baird, D. Holowka and B. Goldstein. Binding Mechanisms of PEGylated Ligands Reveal Multiple Effects of the PEG Scaffold. Biochemistry 47(3): 1017-1030, 2008.

Das, R., S. Hammond, D. Holowka and B. Baird. Real-Time Cross-Correlation Image Analysis of Early Events in IgE Receptor Signaling. Biophys. J. 94(12): 4996-5008, 2008.

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2007

Sengupta, P., B. Baird and D. Holowka. Lipid rafts, fluid/fluid phase separation, and their relevance to plasma membrane structure and function. Semin. Cell Dev. Biol. 18(5): 583-590, 2007.

Dong, R., S. Krishnan, B.A. Baird, M. Lindau and C.K. Ober. Patterned Biofunctional Poly(acrylic acid) Brushes on Silicon Surfaces. Biomacromolecules 8(10): 3082-3092, 2007.

Sil, D., J.B. Lee, D. Luo, D. Holowka and B. Baird. Trivalent Ligands with Rigid DNA Spacers Reveal Structural Requirements for IgE Receptor Signaling in RBL Mast Cells. ACS Chem. Biol. 2(10): 674-684, 2007.

Holowka, D., D. Sil, C. Torigoe and B. Baird. Insights into immunoglobulin E receptor signaling from structurally defined ligands. Immunol. Rev. 217(1): 269-279, 2007.

Moran-Mirabal, J.M., A.J. Torres, K.T. Samiee, B.A. Baird and H.G. Craighead. Cell investigation of nanostructures: zero-mode waveguides for plasma membrane studies with single molecule resolution. Nanotechnology 18(19): 195101-195111, 2007.

Baumgart, T., A.T. Hammond, P. Sengupta, S.T. Hess, D.A. Holowka, B.A. Baird and W.W. Webb. Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles. PNAS 104(9): 3165-3170, 2007.

Sengupta, P., D. Holowka and B. Baird. Fluorescence Resonance Energy Transfer between Lipid Probes Detects Nanoscopic Heterogeneity in the Plasma Membrane of Live Cells. Biophys. J. 92(10): 3564-3574, 2007.

Wu, M., T. Baumgart, S. Hammond, D. Holowka and B. Baird. Differential targeting of secretory lysosomes and recycling endosomes in mast cells revealed by patterned antigen arrays. J. Cell Sci. 120(17): 3147-3154, 2007.

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2006

Senaratne, W., K. Takada, R. Das, J. Cohen, B. Baird, H.D. Abruna and C.K. Ober. Dinitrophenyl ligand substrates and their application to immunosensors. Biosens. Bioelectron. 22(1): 63-70, 2006.

Burns A., P. Sengupta, T. Zedayko, B. Baird and U. Wiesner. Core-Shell Fluorescent Silica Nanoparticles for Chemical Sensing: Moving towards Single Particle Laboratories. Small 2(6): 723-726, 2006.

M.J. Swamy, L. Ciani, M. Ge, A K Smith, D. Holowka, B. Baird and J.H. Freed. Coexisting Domains in the Plasma Membranes of Live Cells Characterized by Spin Label ESR Spectroscopy. Biophys J. 90(12): 4452-4465, 2006.

Senaratne, W., P. Sengupta, V. Jakubek, D. Holowka, C.K. Ober and B. Baird. Functionalized Surface Arrays for Spatial Targeting of Immune Cell Signaling. J. Am. Chem. Soc. 128(17): 5594-5595, 2006.

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2005

Larson, D.R., J.A. Gosse, D. Holowka, B. Baird and W.W. Webb: Temporally resolved interactions between antigen-stimulated IgE receptor s and Lyn kinase on living cells. J. Cell Biol. 171(3): 527-536, 2005.

Joralemon, M.J., N.L. Smith, D. Holowka, B. Baird and K.L. Wooley: Antigen-Decorated Shell Cross-Linked Nanoparticles: Synthesis, Characterization, and Antibody Interactions. Bioconjug. Chem. 16(5): 1246-1256, 2005.

Holowka, D., J.A. Gosse, A.T. Hammond, X. Han, P. Sengupta, N.L. Smith, A. Wagenknecht-Wiesner, M. Wu, R.M. Young and B. Baird: Lipid segregation and IgE receptor signaling: A decade of progress. Biochim. Biophys. Acta. 1746(3): 252-259, 2005.

Gosse, J.A., A. Wagenknecht-Wiesner, D. Holowka and B. Baird: Transmembrane Sequences are Derminants of Immunoreceptor Signaling. J. Immunol. 175(4): 2123-2131, 2005.

Senaratne, W., C. Harnett, P. Sengupta, B. Baird, H.G. Craighead and C.K. Ober: Molecular Templates for Bio-specific Recognition by Low-Energy Electron Beam Lithography. NanoBiotechnology 1(1): 23-34, 2005.

Hammond, A.T., F.A. Heberle, T. Baumgart, D. Holowka, B. Baird and G.W. Feigenson: Crosslinking a lipid raft component triggers liquid ordered-liquid disordered phase separation in model plasma membranes. PNAS, 102(18): 6320-6325, 2005.

Andruzzi, L., W. Senaratne, A. Hexemer, E.D. Sheets, B. Ilic, E.J. Kramer, B.A. Baird and C.K. Ober: Oligo(ethylene glycol) containing polymer brushes as Bio-selective surfaces. Langmuir 21(6): 2495-2504, 2005.

Ow, H., D.R. Larson, M. Srivastava, B.A. Baird, W.W. Webb and U. Wiesner: Bright and Stable Core-Shell Fluorescent Silica Nanoparticles. Nano Lett. 5(1): 113-117, 2005.

Edel, J.B., M. Wu, B. Baird and H.G. Craighead: High Spatial Resolution Observation of Single-Molecule Dynamics in Living Cell Membranes. Biophys. J. 88(6): L43-L45, 2005.

Young, R.M., X. Zheng, D. Holowka and B. Baird: Reconstitution of Regulated Phosphorylation of FcepsilonRI by a Lipid Raft-excluded Protein-tyrosine Phosphatase. J. Biol. Chem. 280(2): 1230-1235, 2005.

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2004

Naal, R.M.Z.G., J. Tabb, D. Holowka and B. Baird: In situ measurement of degranulation as a biosensor based on RBL-2H3 mast cells. Biosens. Bioelectron. 20(4): 791-796, 2004.

Wu, M., D. Holowka, H.G. Craighead and B. Baird: Visualization of plasma membrane compartmentalization with patterned lipid bilayers. PNAS 101(38): 13798-13803, 2004.

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2003


Baird, E.J., D. Holowka, G.W. Coates and B. Baird: Highly Effective Poly(Ethylene Glycol) Architectures for Specific Inhibition of Immune Receptor Activation.  Biochemistry 42(44): 12739-12748, 2003.

Pyenta, P., P. Schwille, W.W. Webb, D. Holowka and B. Baird: Lateral Diffusion of Membrane Lipid-Anchored Probes Before and after Aggregation of Cell Surface IgE-Receptors.  J. Phys. Chem. A  107: 8310-8318, 2003.

Ge, M., A. Gidwani, H.A. Brown, D. Holowka, B. Baird and J.H. Freed: Ordered and Disordered Phases Coexist in Plasma Membrane Vesicles of RBL-2H3 Mast Cells. An ESR Study.  Biophys. J. 85(2): 1278-1288, 2003.

Gidwani, A., H.A. Brown, D. Holowka and B. Baird: Disruption of lipid order by short-chain ceramides correlates with inhibition of phospholipase D and downstream signaling by FceRI. J. Cell Sci. 116(15): 3177-3187, 2003.

Young, R.M., D. Holowka and B. Baird: A lipid raft environment enhances Lyn kinase activity by protecting the active site tyrosine from dephosphorylation. J. Biol. Chem. 278(23): 20746-20752, 2003.

Naal, R.M.Z.G., E.P. Holowka, B. Baird and D. Holowka: Antigen-Stimulated Trafficking from the Recycling Compartment to the Plasma Membrane in RBL Mast Cells.  Traffic 4(3): 190-200, 2003.

Orth, R., M. Wu, D.A. Holowka, H.G. Craighead and B.A. Baird: Mast Cell Activation on Patterned Lipid Bilayers of Subcellular Dimensions. Langmuir 19: 1599-1605, 2003.

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2002


Paar, J.M., N.T. Harris, D. Holowka and B. Baird: Bivalent Ligands with Rigid, Double-Stranded DNA Spacers Reveal Structural Constraints to Signaling by FceRI. J. Immunol. 169(2): 856-864, 2002.

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2001

Gidwani, A., D. Holowka and B. Baird: Fluorescence Anisotropy Measurements of Lipid Order in Plasma Membranes and Lipid Rafts from RBL-2H3 Mast Cells. Biochemistry 40: 12422-12429, 2001.

Pyenta, P.S., D. Holowka and B. Baird: Cross-Correlation Analysis of Inner Leaflet-Anchored Green Fluorescent Protein Co-Redistributed with IgE Receptors and Outer Leaflet Lipid Raft Components.  Biophys. J. 80(5): 2120-2132, 2001.

Hong-Geller, E., D. Holowka, R.P. Siraganian, B. Baird and R.A. Cerione: Activated Cdc42/Rac reconstitutes FceRI-mediated Ca2+ mobilization and degranulation in mutant RBL mast cells. PNAS 98(3): 1154-1159, 2001.
 
Holowka, D. and B. Baird: FceRI as a paradigm for a lipid raft-dependent receptor in hematopoietic cells.  Sem. Immunol. 13: 99-105, 2001.

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2000

Field, K.A., J.R. Apgar, E. Hong-Geller, R.P. Siraganian, B. Baird and D. Holowka: Mutant RBL mast cells defective in FcepsilonRI signaling and lipid raft biosynthesis are reconstituted by activated rho-family GTPases.  Mol. Biol. Cell 11: 3661-3673, 2000.


Fridriksson, E.K., A. Beavil, D. Holowka, H.J. Gould, B. Baird and F.W. McLafferty: Heterogeneous glycosylation of immunoglobulin E constructs characterized by top down high-resolution 2-D mass spectrometry.  Biochemistry 39: 3369-3376, 2000.
 
Holowka, D., E.D. Sheets and B. Baird: Interactions between FceRI and detergent-resistant membrane domains (rafts) are regulated by the actin cytoskeleton.  J. Cell Sci. 113: 1009-1019, 2000.

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1999

Baird, B., E.D. Sheets and D. Holowka: How does the plasma membrane participate in cellular signaling by receptors for immunoglobulin E? Biophysical Chem. 82: 109-119, 1999.
 
Sheets, E.D., D. Holowka and B. Baird: Critical role for cholesterol in lyn-mediated tyrosine phosphorylation of FceRI and their association with detergent-resistant membranes. J. Cell Biol. 145: 877-887, 1999.

Fridriksson, E.K., P. Shipkova, E.D. Sheets, D. Holowka, B. Baird and F.W. McLafferty: Quantitative analysis of phospholipids in functionally important membrane domains from RBL-2H3 mast cells using tandem high-resolution mass spectrometry. Biochemistry 38: 8056-8063, 1999.

Ge, M., K. A. Field, R. Aneja, D. Holowka, B. Baird and J.H. Freed: ESR characterization of liquid ordered phase of detergent resistant membranes from RBL-2H3 Cells. Biophys. J. 77: 925-933, 1999.
 
Fridriksson, E.K., B. Baird and F.W. McLafferty: Electrospray mass spectra from protein electroeluted from SDS-PAGE Gels. J. Am. Soc. Mass Spectrom. 10: 453-455, 1999.
 
Field, K.A., D. Holowka and B. Baird: Structural aspects of the association of FceRI with detergent resistant membranes.  J. Biol. Chem.  274: 1753-1758, 1999.

Guo, C., K.E. Georgiadis, S.K. Dower, D. Holowka and B. Baird: Interleukin 1 (IL-1) causes changes in lateral and rotational mobilities of IL-1 type 2 receptors. Biochemistry 38: 1618-1625, 1999.
 
Sheets, E.D., D. Holowka and B. Baird: Membrane organization in IgE receptor signaling. Curr. Opin. Chem. Biol, 3: 95-99, 1999.

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1998

Baird, B., K.A. Field and D. Holowka: IgE receptor signaling utilizes membrane domains. In Biol. Skr. Dan. Vid. Selsk.  49:147-151, 1998.

Xu, K., R.M. Williams, D. Holowka and B. Baird: Stimulated release of fluorescently-labeled IgE fragments that efficiently accumulate in secretory granules after endocytosis in RBL-2H3 mast cells. J. Cell Sci.  111: 1385-2396, 1998.

Field, K.A., D. Holowka and B. Baird: FceRI signaling in specialized membrane domains. In Signal Transduction in Mast Cells and Basophils  (Ed. E. Razin and J. Rivera) Springer-Verlag, New York; 1998.
 
Xu, K., B. Goldstein, D. Holowka and B. Baird: Kinetics of multivalent antigen DNP-BSA binding to IgE-FceRI in relationship to stimulated tyrosine phosphorylation of FceRI. J. Immunol. 160: 3225-3235, 1998.

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1997

Pierini, L.M., N.T. Harris, D. Holowka and B. Baird: Evidence supporting a role for microfilaments in regulating the coupling between poorly dissociable IgE-FceRI aggregates and downstream signaling pathways. Biochemistry 36: 7447-7456, 1997.

Field, K.A., D. Holowka and B. Baird: Compartmentalized activation of the high affinity IgE receptor within membrane domains. J. Biol. Chem. 272: 4276-4280, 1997.

Harris, N.T., B. Goldstein, D. Holowka and B. Baird: Altered patterns of tyrosine phosphorylation and Syk activation for sterically restricted cyclic dimers of IgE-FceRI. Biochemistry 36: 2237-2242, 1997.

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1996

Pierini, L.M., D. Holowka and B. Baird: FceRI-mediated association of 6 mM beads with RBL-2H3 mast cells results in exclusion of signaling proteins from the phagosome and abrogation of normal downstream signaling. J. Cell Biol. 134: 1427-1439, 1996.

Feder, T.J., I. Brust-Mascher, J.P. Slattery, B. Baird and W.W. Webb: Constrained Diffusion or Immobile Fraction on Cell Surfaces: a New Interpretation.  Biophys. J. 70: 2767-2773, 1996.

Subramanian, K., D. Holowka, B. Baird and B. Goldstein: The Fc segment of IgE influences the kinetics of dissociation of a symmetrical bivalent ligand from cyclic dimeric complexes.  Biochemistry 35:  5518-5527, 1996.

Hashemi, B.B., J.P. Slattery, D. Holowka and B. Baird: Sustained T cell receptor-mediated Ca2+ responses rely on dynamic engagement of receptors.  J. Immunol. 156: 3660-3667, 1996.

Holowka, D. and B. Baird: Antigen-mediated IgE receptor aggregation and signaling:  A window on cell surface structure and dynamics.  Ann. Rev. Biophys. Biomolec. Struct. 25: 79-112, 1996.

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1995

Guo, C., S. Dower, D. Holowka and B. Baird: Fluorescence resonance energy transfer reveals IL-1-dependent aggregation of IL-1 type I receptors that correlates with receptor activation.  J. Biol. Chem.  270: 27562-27568, 1995.
 
Field, K.A., D. Holowka and B. Baird: FceRI-mediated recruitment of p53/56lyn to detergent-resistant membrane domains accompanies cellular signaling. Proc. Natl. Acad. Sci. USA 92: 9201-9205, 1995.

Posner, R.G., K. Subramanian, J. Thomas, T. Feder, D. Holowka, B. Baird and B. Goldstein: Simultaneous crosslinking by two non-triggering bivalent ligands causes synergistic signaling of IgE-FceRI complexes. J. Immunol.  155: 3601-3609, 1995.

Chang, E.-Y., S.-Y. Mao, H. Metzger, D. Holowka and B. Baird: Effects of subunit mutation on the rotational dynamics of FceRI, the high affinity receptor for IgE, in transfected cells. Biochemistry 34: 6093-6099, 1995.

Chang, E.-Y., Y. Zheng, D. Holowka and B. Baird: Alteration of lipid composition modulates FceRI signaling in RBL-2H3 Cells. Biochemistry 34: 4376-4384, 1995.

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1994


Thomas, J.L., D. Holowka, B. Baird and W.W. Webb: Large-scale co-aggregation of fluorescent lipid probes with cell surface proteins. J. Cell Biol. 125: 795-802, 1994.

Baird, B., Y. Zheng and D. Holowka: Structural mapping of IgE-FceRI, an immuno-receptor complex. Accts.  Chem.  Res.  26: 428-434, 1993.

Weetall, M., D. Holowka and B. Baird: Heterologous desensitization of FceRI on RBL Cells. J. Immunol. 150: 4072-4083, 1993.

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1993

Marano, N., M. Liotta, J.P. Slattery, D. Holowka and B. Baird: FceRI and the T cell receptor for antigen activate similar signaling pathways in T cell - RBL cell hybrids. Cellular Signalling 5: 155-167, 1993.

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1992

Posner, R.G., B. Lee, D.H. Conrad, D. Holowka, B. Baird and B. Goldstein: Aggregation of IgE-receptor complexes on rat basophilic leukemia cells does not change the intrinsic affinity but can alter the kinetics of the ligand-IgE interaction. Biochemistry 31: 5350-5356, 1992.

Zheng, Y., B. Shopes, D. Holowka and B. Baird: Dynamic conformations compared for IgE and IgG1 in solution and bound to receptors.  Biochemistry 31: 7446-7456, 1992.

Holowka, D. and B. Baird: Recent evidence for common signalling mechanisms among immunoreceptors that recognize foreign antigens. Cellular Signalling 4: 339-349, 1992.

Myers, J., D. Holowka and B. Baird: Rotational motion of monomeric and dimeric immunoglobulin E-receptor complexes.  Biochemistry 31: 567-575, 1992.

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1991

Erickson, J., R. Posner, B. Goldstein, D. Holowka and B. Baird: Analysis of ligand binding and crosslinking of receptor in solution and on cell surfaces:  immunoglobulin E as a model system.  In Biophysical and Biochemical Aspects of Fluorescence Spectroscopy (Ed. T.G. Dewey) Plenum Press, New York.  169-195, 1991.
 
Posner, R., J. Erickson, D. Holowka, B. Baird and B. Goldstein: Dissociation kinetics of bivalent hapten - immunoglobulin E aggregates in solution. Biochemistry 30: 2348-2356, 1991.
 
Erickson, J., R.G. Posner, B. Goldstein, D. Holowka and B. Baird: Bivalent ligand dissociation kinetics from receptor-bound immunoglobulin E:  Evidence for a time dependent increase in ligand rebinding at the cell surface.  Biochemistry 30: 2357-2363, 1991.
 
Keegan, A., C. Fratazzi, B. Shopes, B. Baird and D. Conrad: Characterization of monoclonal rat anti-mouse IgE antibodies and their use to map the site on mouse IgE that interacts with FceRI and FceRII. Molec. Immunol. 28: 1149-1154, 1991.
 
Labrecque, G., D. Holowka and B. Baird: Characterization of increased K+ permeability associated with the stimulation of receptors for immunoglobulin E on rat basophilic cells. J. Biol. Chem. 266: 14912-14917, 1991.
 
Zheng, Y., B. Shopes, D. Holowka and B. Baird: Conformation of IgE bound to receptor and in solution. Biochemistry 30: 9125-9131, 1991.

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1990

Kane, P., D. Holowka and B. Baird: Characterization of model antigens composed of biotinylated haptens bound to avidin. Immunol. Invest. 19: 1-25, 1990.

Narasimhan, V., D. Holowka and B. Baird: A guanine nucleotide-binding protein participates in IgE receptor-mediated activation of endogenous and reconstituted phospholipase A2 in a permeabilized cell system.  J. Biol. Chem. 264: 1459-1464, 1990.
 
Holowka, D., T. Wensel and B. Baird: A nanosecond fluorescence depolarization study on the segmental flexibility of receptor-bound IgE. Biochemistry 29: 4607-4612, 1990.
 
Holowka, D. and B. Baird: Structure and function of the high affinity receptor for immunoglobulin E. In Cellular and Molecular Mechanisms of Inflammation: Receptors of Inflammatory Cells, C.C. Cochrane and M. Gimbrone, eds.. Academic Press, Inc., Orlando, FL.  173-197, 1990.
 
Narasimhan, V., D. Holowka and B. Baird: Microfilaments regulate the rate of exocytosis in rat basophilic leukemia cells. Biochem. Biophys. Res. Comm. 171: 222-229, 1990.
 
Shopes, B., M. Weetall, D. Holowka and B. Baird: Recombinant human IgG1-murine IgE chimeric immunoglobulins: Construction, expression, and binding to human FcgRI and FcgRII. J. Immunol.  145: 3842-3848, 1990.
 
Weetall, M., B. Shopes, D. Holowka and B. Baird: Mapping the site of interaction between murine IgE and its high affinity receptor with chimeric immunoglobulins. J. Immunol.  145: 3849-3854, 1990.
 
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